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1.
Generally refers to 1984 model spoke wheels wrapped with Vogue brand tires.
"Tippin' on fo'-fo's (four fours)" from Mike Jones' Still Tippin' (Featuring Slim Thug & Paul Wall)
by elphKOTM March 08, 2005
 
2.
a .44 caliber magnum pistol
shits is gonna get murderous, nigga betta bring the four-four
by rocky June 16, 2006
 
3.
A .44 caliber hand gun.
"Who da fuck wanna war? I got a four four."
- 50 Cent
by Kurtis Kennedy January 20, 2004