A barrier that surrounds many high school girls who are too attached to their female friends. Due to the fact that they are constantly surrounded by judgemental girlfriends (who may or may not be giggling), it proves difficult to ask out said girl due to the excess of females surrounding her. Thus the estrogen barrier.
Guy 1: "God damn! How am I supposed to ask out Alicja when she's got her estrogen barrier up?!"

Guy 2: "I hear that the best time to get those women is just before they go to bed at night, or RIGHT after they get out of the shower. Any other time and you're fucked.
by Guy 3 February 4, 2009
Get the Estrogen Barrier mug.