Top Definition
A fail among fails, the failiest fail in all failness. Epic masterfails can only be executed by an accomplished failure, and usually results in shame, injury, humiliation, death, dismemberment, stds, ect. Epic Masterfails are something usually only witnessed once in a lifetime, so if you see one be sure to tell EVERYONE about it, because you'll never see another.
"Yo dawg George Bush's presidency was such an Epic Masterfail n shit."
by MackMrOrange April 25, 2009

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