The possessive form of En is 'Es'.
2. The being of light telepathically adjusted the imperfect neurons in es human subject. En was pleased with what en saw.
In the first example, the child probably had a gender. If that gender was known, it would be perfectly reasonable to label the child he, she, him or her. However, in the second example, the being of light had no genitals. Therefore, es gender was irrelevant.
Under no circumstances should the ambiguous terms 'their' or 'them' be used in the singular context again, or 'it' in reference to a non-human being.
Guy 2: How the hell did that happen?
Guy 1: We were banging on top of the deep freeze and she had a wicked case of EN, i swear they were harder than a diamond in an ice storm!