A meister of dweebiness; someone who has mastered the art of being a dweeb. A dork, nerd, etc. who's interested in totally geek-ish stuff that only real losers would know anything about, like the Internet or video games.
Opposite of "hunkmeister".
"I'd rather take a math test than talk to that geekosaurus Melvin."
"Tell me about it, what a total dweebmeister."