Top Definition
Marijuana that is so good, your friends make it disappear in the night. Ghostly actions happened to your dope! Rasta reference emulated into word.
First Stoner: "Hey man, where's that great smoke from last night?" "What kind was dat anyway?"
Second Stoner: "Dat was my Duppy Weed!"
by monkeygirlmarley December 23, 2010

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