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2.
the act of pooping or taking a dump.
boy1: hey were where you last night at the party?
boy2: i had to duke it out.
boy1: oh.
by thunder_storm996 July 10, 2008
 
1.
To fight, usually fist fight. Probably from John 'the Duke' Wayne movies where he would always end up fighting with someone.
You want to teach him a lesson, duke it out.
by BobLoblaws October 13, 2006