Top Definition
a disease that infects mostly males.
however, rare cases have been discovered among females.

males who have been infected are generally known as douchebags.
females, likewise, are known as douchebaguettes.

smart-ass comments at inappropriate times, lack of a significant amount of brain cells, sexual urges with people you just met, sexual urges with people you've always known, sexual urges with old people, a constant need of multiple sexual partners, a constant demand for sexual favors at inappropriate times, a need to publicly talk about recent sexual acts, a need to publicly provide evidence of recent sexual acts, and of course a blatant disregard for the feelings of the "partner-of-the-moment".
also, rare cases of herpes have indirectly resulted from this wide-spread disease.
Did you hear that Matt and Katrina hooked up on Friday? He was passing around her underwear at lunch talking about what a slut she is.

Yeah, dude's totally a victim of Douche Flu.
by stegosaurus May 19, 2009
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