When somebody ruins something or when somebody will ruin something because they are not good enough at it.. Whether it is a game, joke or saying. Most commonly used in a basketball game: "Yo don't suss the run with your game."
Yo, stop sussin the run with your jokes.

Don't suss the run with that weak ass shot of yours.
by Bink Bink Mink November 14, 2011
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