Top Definition
Dom Syndrome is a mental illness that seems very similar to Down Syndrome but without the obvious physical features. It can be brought on by smoking large quantities of weed. They tend to think that they are God's gift to women without any actual evidence that this is the case.
Female 1 "Why is that boy dancing at me in that peculiar fashion? I wish that he would stop."
Female 2 " Just smile at him and nod. That boy has Dom Syndrome"
Female 1 "Oki, but if he touches me then I'm slapping him"
by ihatemymeds May 24, 2011

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