Top Definition
A condition in which the affected person(s) compulsively swears, talks of beastiality, incest, their fake homosexuality, fecal waste, urination, boobies and masturbation due to obsession with Blink-182's and their guitarist, Tom DeLonge's live performances, interviews and random recordings.
Doctor: Sir, our diagnosis on you is simply DeLonge's Syndrome.

Guy: Shitfuck! That gets me horny! Where's my dog!?
by eldonge13 March 31, 2010
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