To do work on some shit. To get shit done. Used for emphasis on how hard you're about to go.
Dexter is about to Dassle that dude!

Dude, I can't go out tonight, I gotta Dassle on some Homework.

Ok, show starts in 2 hours, we gotta dassle this vodka and get the fuck out of here
by Johan Kvvelter December 07, 2011

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