Top Definition
1. A person with downs syndrome

2. A retard
1. that poor guy is a DSer

2. Dude, your a Dser

by BigJohnson April 03, 2007
1 more definition
6 Words related to DSer
(n - noun)DS'er: Downstairs Shitter. A person who shits downstairs.
Adam is such a Ds'er.
by Mary, Mike, Oliver November 05, 2006

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