DDHD stands for Dumb Depressed Hoe Desiese and is acotiated with thots/ E-girls/ sluts. But the word is commonlly used in a joking way.

This term was coined by a professional in the feild on Instagram and the 1st official case of some one having the Desiese was Liette Last Name Redacted
Yo man why are u coming all up in here with your DDHD?!
by GGDash October 14, 2019
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taken from Soulja Boy's song 'Yahhhh!', DDHD is an acronym for 'Doo Doo Head Dummy'. it's a fun and easy way to insult someone to their face and have them not know exactly how mean you are being.
Preppy Loser: Oh ehm gee, like, you're such a fricking prude.

Normal Person: Bitch.

Preppy Loser: GASP! Ms. Cassidy! She called me a bitch! Give her saturday detention!

OR

Preppy Loser: Oh ehm gee, like, you're such a fricking prude.

MLIA-er: Oh, well, at least i'm not a DDHD.

Preppy Loser: ugh. loser.
by i don't like cussing. :3 November 22, 2009
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Phase three of ADD, ADHD, = DDHD. distraction domination hyper-active disorder.
Tommy spins around in his chair and rambles due to his severe care of DDHD.
by eabsy September 3, 2008
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