Dick Of Unusual Size. An adaptation from the popular film and novel The Princess Bride where the acronym R.O.U.S. represents Rodents of Unusual Size.
Ozone: Turbo, why did you just fall down?
Turbo: Sorry Ozone, I just tripped on my D.O.U.S.
Ozone: Yeah, that thing is no good, my mom has also been complaining about the negative side effects of your D.O.U.S.