When your eyes dry up thus causing them to appear red and bloodshot. The term comes from the common smoking term cotton mouthed , which is when the smokers mouth dries up as if they were chewing on cotton balls.
Kind sir pass me the eye drop my eyes have become quite cottoneyed
by Veitnam VW July 22, 2013
1 more definition
Archaic description for a blind man, referencing how the eyes appear fully white (for instance advanced cases of cataracts or glaucoma)
From Steinbeck's East of Eden "...the crooked little cotton-eyed piano player stood...waiting for a sound to tell him where she was.
by Fetus2494 June 27, 2015