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When you can't date, or have sex, with someone because they're the friend of someone you dated, or had sex with. Most commonly experienced when one wants to date one of an ex's friends, but they can't, because they're the friend of their ex.
"-I wanna date Jenny, but she's my ex's best friend, so I can't.
-You my friend, have been cockblocked by association."
by DarkwingMotherfuckinDuck March 19, 2010