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When a person is born with a cleft lip and it's so bad that it makes them really ugly and gross looking for life. It's a very pyschological syndrome that the person who has it isn't aware of how gross they really are.
BozN: See that Crystal chick?

Mike: Yah, makes me sick to my stomach

BozN: I hear you, she has Cleft Lip Syndrome, that's why she is nasty and thinks she's the shit.

Mike: Yeah, poor girl.
by JOSHEEEEE March 04, 2009
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