Top Definition
A genetic abnormality affecting a large number of women in modernized nations. Mainly features a large and overweight midsection/upper thighs while the remainder of the physique is still fit in nature.

Not a lot can be done to rectify this and it is a shame when an otherwise hot girl has been afflicted.

Refer to the movie chicken run for visual examples.
"Check out that girl, she'd be hot if she didn't have chicken run syndrome"
by Bateman23 April 17, 2010

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