Top Definition
Occurs when one masturbates and then fails to wash his/her hands then greets someone with a firm handshake.
"Dude, I jerked off earlier and forgot to wash my hands. Then, I met my girl's parents and totally gave them a cheesecake handshake."
by Team Awesomest May 07, 2008
5 Words related to Cheesecake Handshake

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