The biggest joke in Hollywood, and is incredibly high all the time, while banging his full time prostitutes.
Guy 1: "How much cocaine do you think Charlie Sheen is on right now?"

Guys 2: "I don't know for sure, but probably enough to kill two and a half men"
by Winning Tiger Blood March 17, 2011
Charlie Sheen -noun. A man who bangs average looking prostitutes (goddesses), uses methamphetamine (tiger blood), and appears on national television obviously high/tweaking (winning).
I need AA, NA, Valtrex, a new publicist, and an intervention from Dr. Drew. I've clearly pulled a Charlie Sheen this weekend.
by Bad Ass Frank March 03, 2011
A drug that if you try it once, you will die. Your face will melt off and your children will weep over your exploded body.
What is with you today?

I'm high on Charlie Sheen. #WINNER
by tigerblood March 02, 2011
I'm Charlie Sheen! "WINNING"
by whitey#15 March 19, 2011
I'm going to Charlie Sheen my Calc 2 exam.
by stressed college student March 14, 2011
It's a drug. Only Winners take.
Kate: I heard that Tommy died this weekend. What happened?

Bob: I heard he tried some Drug called "Charlie Sheen" I guess his face melted off and his children were crying because his body exploded tiger blood all over the walls!!

Kate: Wow!! Crazy stuff.
by warlock11 March 04, 2011
a winner
charlie sheen is not losing
by aNOMNOMNOMynus April 13, 2011

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