Cannonball Run Share definition Flag 1.driving from coast to coast of the United States as fast as possible, often to break a record Alex Roy recently broke the Cannonball Run in 31 hours, using a GPS system and police detector to avoid the police. Cannonball Run by karrot January 6, 2009 0 0 Get merch Get the Cannonball Run mug. Buy Now — $32.95 See more merch