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1.
Sometimes pronounced as Buff-len and sometimes as by-fu-gull-en. However, they both mean the same.

Bisexual fucking ugly alien
that guy is such a byfuglien
by unknown definitioner May 09, 2010
 
2.
by - two
fugly - fucking ugly
ien - to be.

to be too fucking ugly.... just ghastly.
OMG DUDE DID YOU SEE THAT BYFUGLIEN?!
by deepfri February 08, 2010