Top definition
A scientific theory which explains that regularly eating butter, even a small pat, will eventually turn you into a fat butterball.
At the 10 year High School Reunion.....

Gerard: Hey check out Sylvia, she's a total hefer! She used to be hot, what happened?

Chuck: Dude, It's called the Butterball Effect, all those empty fat calories have wreaked their damnable havoc on her once fine physique.

Gerard: Say what now?
by Mr. Softey January 25, 2009
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