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1.
A combination of Drew Brees and Jesus. Meant to reflect the near miraculous play of New Orleans Saints quarterback Drew Brees during the 2009-2010 NFL season.
The Saints beat the Patriots 38 - 17, Praise Breesus!
by WhoDat! Army December 02, 2009
 
2.
The nickname given to New Orleans Saints quarterback Drew Brees during his phenomenal 2009-2010 season. It parallels that Brees is saving and uplifting the great city of New Orleans, just as Jesus once saved his people.
Sean: Fuck, the Saints are down 21 with ten minutes to go, and I bet $50 on this game.

Stuart: It's alright, Breesus is gonna torch these fuckers with three touchdown passes.
by ridgeraider December 31, 2009