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An annoying way to say you're going to the bathroom, often used in WoW but has been used less frequently over the years (thankfully)
Gaydude123: Brb bio
Gayguy321: Dude just say you have to take a shit
by GM8 October 03, 2010
79 80
Usually when people, mostly girls, are in the mist of fight. And one of the girls is like "B.I.O. (Bring It On)!" Don't piss off that girl right there! She will lash out.
Stacy: "B.I.O. BITCH! Don't mess with me!"
Jean: "HA! Try me!"
by SURFTIME9 June 13, 2011
1 4
slang for cocaine.
angel: hey dude what'd you do today?
warren: bios
angel: wtf dude, how much did you grab?
warren: half g
angel: sick
by OfficialTripz April 04, 2010
5 26
A polite way of saying that you're going to the bath room.
Stands for Be In the "Office".
Guy one: "Hey man I just ate a ton of Mexican food, BIO break."
Guy two: "Dude, nasty..."
by Capt Anarchy May 05, 2009
40 61
Abbreviation of biodiesel.
My Benz runs on bio.
by jahmiller October 19, 2010
10 37
BIO is an acronym of the phrase BITCH ITS ON!

it can also be substituted for bring it on but is slightly less effective.
girl1: i bet guys like me more than they like you!

girl2: BIO!
by twentyone31 March 05, 2010
10 40
Beauty Inside and Out
From Tyra Banks show: beauty comes from inside and out! BIO!
by cng413 May 24, 2010
18 51