False self-diagnosis of High-functioning Autism (asperger's syndrome), mostly used by nerds with no social skills as an excuse for the complete failure to understand irony in real life.

Might also refer to a slightly autistic person with a nice ass

Assburgers was mentioned in southpark first S15 E8.
Cartman: Are you serious? How can there be- Oh my God! You're saying I have ass burgers??

Nurse Bronski: This doesn't make sense. Are you trying to sneak food into the school or something?

Cartman: What are you talking about?? I got vaccinated from the school, and now clearly I have Assburgers!

Nurse Bronski: Very funny!

Cartman: Well I'm glad you think Assburgers Syndrome is funny! Just note my condition on your records there!
by Peppi_Dufter September 19, 2023
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