Appleton natives include some fucked up people, such as Harry Houdini, Joseph McCarthy, and The John Birch Society. Willem Dafoe also hails from Appleton.
Appleton happens to host the longest Flag Day Parade and the largest annual ska concert in the Midwest - "SKAppleton".
As for moments in history, Appleton's Valley Fair Shopping Center (now almost completely demolished) was one of the first enclosed shopping malls in the United States. Appleton was also the first city in Wisconsin to have a telephone and the first city outside of the East Coast to have incandescent light.
No way man Appleton is red-neck territory.