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The extreme of going apeshit. To completely lose one's mind in a violent manner, or when used to describe a situation, the act of descending into complete chaos.
When I found out that my entire project had been deleted, I went completely apeshit bananas on everyone that had touched my computer in 24 hours.

By the time the riot police got there, everything was already apeshit bananas.
by Mr. Puggles September 26, 2011