African Mudhole Share definition Flag the act of fisting someone's butt and then sticking that same fist in your mouth, eating the shit "Joanna got really stressed out when my fist got suck in her ass when I was giving her an African Mudhole." African Mudhole by Andrew Kline April 30, 2006 0 0 Get merch Get the African Mudhole mug. Buy Now — $32.95 See more merch