Acronym for “Actively Looking For Ass” Mode.

When the sole purpose of your day is to find sex.
Girl 1: “Jessica seems distant and preoccupied this afternoon?”

Girl 2: “Don’t mind her, she’s in full ALFA Mode today.”

Girl 1: "ALFA Mode?"

Girl 2: "Ya, she's actively looking for ass right now."
by KM2103 October 22, 2010
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