Top Definition
The last ten minutes before most of the clubs shut. This is when deperate lonely chumps get off their asses and hit the dance floor seeking easy prey for their sexual needs. During this short period it is not rare to see desperate males going beyond the "2 above - 2 below" points rule that is generally accepted.
Chump 1: "10 to 2 bois! Let's get some pussy on the go!"

Chump 2: "That bird is a 10 to 2 at best."
by Jandy May 05, 2008
1 more definition
1. in reference to how one twists the pickle while smoking meth
"How do i do this?"

"10 to 2 nigga, twist it!"
by SwitchBlade May 29, 2006

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