.44 Caliber Handgun (IE. Desert Eagle, Revolver)
we don't cater to you hoes
Fuck with me, have a hundred motherfuckers at yo' do',
with fo'-fo's

2pac- Deadly combination
by AC December 15, 2003
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fo fo, a .44 calibre gun
nas: "where so many souls go, because of a fo' fo' blast"
by Ace September 23, 2003
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A .44 calibre weapon, especially a handgun like a Smith & Wesson Magnum revolver
Pronounced 'four-four'
I start some trouble everywhere that I go (that I go)
Ask the bouncers in the club cause they know (cause they know)
I start some shit they throw me out the back do' (the back do')
Come back and shoot the club up with a fo fo (a fo fo) - Eminem impersonating Snoop Dogg in Bitch Please II
by Guy Martin September 2, 2007
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A gun; gat

Usually used to shoot people
"I lit him up with my fo-fo"
by Vinny Amaru July 5, 2006
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The sound or noise which you get from humping a inanimate object..
*Greg humps pillow* Fo fo fo
by Greghill May 11, 2010
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Fo' Fo' is slang for fourty four which is known to be a fourty four magnum which is a gun.
ill take my fo' fo' out an make sure all yo' kids dont grow
by Big Dave November 28, 2003
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