The "Oz" Syndrome is when a guy is stunning looking and confident yet can't get laid because girls think he's a player and a douchebag. Often found alone at home while the less attractive guys are out banging lots of beautiful women. He gets tons of looks from women but very rarely gets past "Hi"

In other words, a "brad pitt" treated like an uggo
"Oz" Syndrome:

Chris "Oz" Ostreicher from American Pie 1 and 2

American Pie (1999)
Chris "Oz" Ostreicher: Suck me beautiful.
College Girl: What did you just say?
Chris "Oz" Ostreicher: Suck me beautiful!
girl laughs
Chris "Oz" Ostreicher: Friends call me Nova as in Casanova.
College Girl: That's pathetic!
Chris "Oz" Ostreicher: Jeez you don't have to laugh at me.

Also hated in real life, from Chris Klein's IMDb page:
"1. Hes a sexist pig

2. Hes an ugly jerk

3. Cannot act to even save his own *beep* life

4. was incredibly Rude to Katie Holmes

5. he thinks hes Gods gift to women

6. Because I *beep* hate his guts.

This guy is the biggest piece of *beep* to ever grace this world. He really needs to bury his head in the sand and just leave it there. That would be his major contribution to society. He has nothing to offer but his arrogance and constant negative attitude. He deserves a slap in his face. Thats all I have to say."
by "Oz"ified November 22, 2009
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