When you take too many prescriptions painkillers and have diarrhea similar to shitting hot tar for several hours
A: Man I had a bad gloop last night after taking my dad's pain pills

B: Dude how are you not dead
by Bigbenis6969 January 7, 2021
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Another term for something that has you acting funny (any sort of drug or something that changed you)
Guy : why are you like this recently?

Guy2 : my bad bro im on that gloop shit
by Hazaz March 13, 2021
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