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Fanny callous 

When a fanny has been worn out so much it forms callouses, typically found on slags or your mum
Your mum has had that many bangs, she's got a serious case of fanny callous.
Fanny callous by Pringlewhore January 12, 2018

pussy callous 

When someone is difficult, stubborn, hard headed, and whines or complains way too much about everything.
Shut the fuck up and stop being a pussy callous- a rough pain in my pussy
pussy callous by Thruple February 20, 2020

Wankers' Callous 

'Wankers' Callous' is loosely defined by the New England Journal of Wankology as "any light abrasion to the shaft of the penis due to either excessive or angry wanking". Whilst cases of Wankers' Callous are historically rare, when it occurs the event can be overwhelming as a short hiatus from masturbation is mandatory.
Doctor: Timmy, I'm afraid you've developed Wankers' Callous. You'll need to lay off the angry wanking; you've wanked your foreskin raw.

Hitler: Doctor Goldman just informed me that mein wankers' callous will not heal until I stop beating mein mutterzerkleinerungsmaschine. All the Jews must pay for this diagnosis.

Timmy: Doctor, your diagnosis made me so angry that I angry wanked my foreskin straight off my penis. It flew out of my hand and down my mother's throat. She died from asphyxiation.
Wankers' Callous by BGH122 May 21, 2010

ass callous 

The toughness built up in and around the rectum of a man due to manual fondling of his butt or from the friction of getting stuck in the butt.
I love building up an ass callous so that guys can run trains on me...
ass callous by LovesItInIt June 22, 2008

Computer callous

A computer callous is located on the heel of your hand, usually the hand you use to move your mouse.

It is usually caused by the heel of your hand being rubbed against the mouse mat for long periods of time, usually during all nighters on the internet.

A computer callous is most often a little more red than your usual skin tone and is quite soft and smooth.
Hoshit, I've been on the computer so long I've aquired a computer callous.
Computer callous by Hollydollie August 21, 2009

nerd callous 

The tough skin that commonly develops on the thumbs of videogamers, as a result of overuse of analog sticks.
Me: "Man, I spent the last 18 hours playing KOTOR 2, and now I've got wicked bad nerd callous..."
nerd callous by Dahrkthorne May 21, 2006