A drug made from a variety of household chemicals mixed with vanilla pudding. The recipe is not clear, but typically involves some combination of bleach, antifreeze, draino, brake fluid, or any of a variety of common chemicals. The mixture is typically ingested in small amounts, but can also be injected in diluted form without the pudding.
The effects vary based on exact recipe and quantity ingested, but range from extreme lethargy and unresponsiveness to mild hallucinations.
Matt: I once knew a teenager whose weed was laced with Puddi and he was put in the ICU. He was released three weeks later, but with irreversable brain damage.

Joren: Dude...<depressed face>

Matt: I know.
by Raise Awareness December 7, 2010
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A dangerous new drug being used by today's youth. Originally made from a number of dangerous chemicals then mixed with a popular japanese dessert (to make edible), it is now mixed with just about any sweet gelatine based product.
Known for being simple to make and being extremely addictive. To date there have been a number of recorded fatalities.
That puddi is going to fuck with your head retard.
by theanonisanon December 7, 2010
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A hardcore drug that just started to hit the scene in mid 2010. Overdoses are almost a given if you try it. More addicting than crack, heroin, jenken, and even meth.
1: Did you hear that Craig is using puddi?
2: Really? What a loser with a capital L.
1: Yeah. He's already missing a few teeth.
by mybrandnewcrocogator December 7, 2010
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A dangerous hallucinogenic which inspires fits of a surreal experience, After mixing the proper blend of advil, niquil and a touch of vicodyn, Puddi has a similar effect to mushrooms, to which many users replied when questioned, "Feels good man". Overuse of this drug causes the brain to degrade and slowly rot while keeping the user in an comatose state while still being consciously awake while not in control of his or her actions. Puddi is incredibly dangerous and should not be used, however it is tragically easy to make by the common teen, and easily mistaken by children as other medicines.
Person 1: Hey man, want to go out tonight? I made some puddi!

Person 2: Aw hell no man. That stuff's messed up!
by BlackHawk6123 December 7, 2010
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refering to the female genitalia as a kitty kat; vagina; snatch; pikachoo
he told me my puddy puddy was the best
by j to the izzle fo shizzle March 11, 2008
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a mix of buddy and pal, more than a best friend. You can count on them forever, they will always be there for you
Hey, they look like puddy's over there
by Tommy Quara October 16, 2020
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On November 30, 4chan was attacked by a popular and unfunny meme called "Giga Puddi". Every post or thread made would have spammed "PUDDI". Surprisingly, this incident made /b/ have a shitstorm of originality and not the usual reposts.

With this other boards on 4chan were flooded with PUDDI, Cheese Pizza and porn.

On December 1st, /b/'s title was "WHY SO PUDDI", and cancer found it's way back to /b/.
PUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDIPUDDI
by Anonymous165484964 December 3, 2010
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