scruffle Share definition Flag V. to rub one's beard against another's skin (usually the neck or face) to show affection As the couple parted ways at the airport, he scruffled her cheek and said, "Call me when you get through security." scruffle by GentlySevere May 10, 2009 0 0 Get merch Get the scruffle mug. Buy Now — $32.95 See more merch