St. Louis Butter Share definition Flag The butt grease and sweat that emerges on a hot August day in St. Louis. If I find out that you gave Sheila an Alabama Hot Pocket, I'll rub a fist full of St. Louis Butter in your eye. St. Louis Butter by Melvin the Sophist September 20, 2007 0 0 Get merch Get the St. Louis Butter mug. Buy Now — $32.95 See more merch