The social indoctrination to the bar scene that occurs on or immediately after one's twenty-first birthday. Typically, the guest of honor on a "21 run" is forced to consume copious amounts of alcohol in a short amount of time. This often results in illness, and, in extreme cases, loss of consciousness. The prototypical "21 run" occurs from 12:01 AM until 2:00 AM on the participant's birthday, this time being the first at which said individual is legally eligible to consume alcohol.
A man's friends who are already twenty-one pick him up and take him to the bars one minute after he turns 21, at 12:01 AM on a "21 run."
by NPR May 25, 2007
celebration of the 21st birthday..usually conists of 21 shots in one night..however this is not easily obtained, and i don't know anyone who has suceeded in consuming 21 shots.
my 21 run is next weekend, let's drink!
by jennlin August 9, 2006
The social indoctrination to the bar scene that occurs on or immediately after one's twenty-first birthday. Typically, the guest of honor on a "21 run" is forced to consume copious amounts of alcohol in a short amount of time. This often results in illness, and, in extreme cases, loss of consciousness. The prototypical "21 run" occurs from 12:01 AM until 2:00 AM on the participant's birthday, this time being the first at which said individual is legally eligible to consume alcohol.
A man's friends who are already twenty-one pick him up and take him to the bars one minute after he turns 21, at 12:01 AM on a "21 run"
by NPR May 25, 2007