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This can be used in any context at any time. It's the ultimate comeback when you can't think of any other better ones. LOL!
Q: What's for dinner tonight?
A: Yo Face

Q: What's that thing that cat's eating
A: Yo face
Yo Face by Falcon2001 February 27, 2017
a comeback that people use when they cant think of anything else more clever to say.
Person 1: Dude you smell awful! where were you last night?
Person 2: Um.... Yo Face!
yo face by Mad_a_Cookie December 6, 2014
A stupid damn comeback that's fun to use.
Nate: Why are you so ugly?
Olivia: YO FACE!
man that guy is such a face i was all yo face then i hit him with a stick and rocks
"Your fat!" Said Bob. "YO face!" I replied.
Yo Face by Hanate0218 November 6, 2018

burn yo face 

To consume hard alcohol, in particular Firefly Sweet Tea
When we were playing Kings, Mike drew a 4, meaning that all girls had to drink. Immediately, Hamid screamed, in Chappelle-esque fashion, "Burn Yo Face"
burn yo face by Dr. Rip February 19, 2010