One of the most common questions that cross men's minds while meeting a hot girl - or a hot anything, according to the subject's sex tastes.
While the complete sentence is well known (can I fuck you?) but can't be used in all occasions, this shortened version, pronounced see-foo, might actually help many hesitant subjects to finally get to the point.
Dude jogging at the park to the girl in shorts running in front of him: "Oh, so you're new here?"
While the bubble on his head spells "And so, cifu?