When a lighthearted comedy or TV show suddenly turns unnecessarily serious and/or introspective.
Well-dressed white people at a trendy bar/club:
Jenny - "I'm having so much fun! Let's all do a shot!"
Johny - "We're all so pretty and happy! That sounds great!"
Janice - "It's so important to live for today! I just found out I have a terminal disease. And my house burned down."
Jenny - "Wow! What a Scrubs Moment! Hopefully it will be resolved after this commercial break!"