1. Historical - White mistress of a slave plantation or any white woman of authority in the southern United States during slavery and the Jim Crow era. 2. Current - Derogatory term for any difficult, bossy or perceived racist/bigoted white woman
"I gotta go clean Miss Ann's house now or I'll never hear the end of it!", "Can you believe Miss Ann had the nerve to order me to work late tonight?", "Hillary Clinton acts like such a Miss Ann!"