An expression used to denote utter surprise, horror and confusion; used in "Return of the Living Dead" when two paramedics encounter a horde of ravenous undead zombies on the hunt for brains.
Can also be used to denote complete disgust with a person or situation.
"Do you hear that?"
(looks down the road at undead hordes of brain eating zombies)
Man1 : "Did you flush the toilet after you dropped that monster dook?"
Man1: "Christ Jesus. You are disgusting."