1. A play on words, with "Charles" being another name for "Chuck". Replace Charles with Chuck and you get the phrase "Chuck Nades!". This term is often uttered by those lacking any prowess in video games, especially nazi zombies.
2. A term used to describe a person possessing unimaginable quantities of undesirable attributes which prevent them from being good at any sort of video game, no matter how hard they may try.
3. A term used to describe someone who will never get this.
Man, looks like we have another Charles Nades, we might as well quit now
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