1 definition by C...punk35

Top Definition
Duffed, or duff someone-to be fucked, or involved in the act of sexual intercoarse.
"Hey man, did you hear the news? last night caitie got duffed!" or "Dammit, my science teacher duffed me on that lab report."
"Are you really gonna duff me like that?"
by C...punk35 February 29, 2012
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