1- to throw out of a window.
2- to switch from MS windows to Linux, Mac OS, or another operating system. As in 'throwing' yourself away from Windows.
3- bluescreen of death. As in the user is thrown out of Windows.
1- The teacher defenestrated the talkative boy's pencil case because he was sick of his constant chatter in class.
2- I defenestrated to Mac OSX recently. Screw M$
3- My computer crashed and defenestrated me. Again.
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