1. Losing your virginity.
2. Having sex with a virgin.
Kelly: I had sex with David last night.
Marie: Really, was he any good?
Kelly: It was really awkward. He told me afterward that he was a virgin.
Marie: So you were the first person to visit his flower shop, eh?
Mark: So, what are you doing tonight man?
Ronnie: I'm visiting the flower shop. Sarah's finally letting me in her pants.
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.
Man, I just watched the funniest nutshot video ever.