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This is an acronym for "Due To Lack Of Interest." The term is popular as a sidebar or casual comment about why something did or did not happen, regarding events in business or personal life. When said out loud the correct method is to name each letter (like this: dee-tee-el-oh-eye), not turn it into a spoken word. Often the term is used in a snarky way.
Two examples:

"The project meeting today is canceled, DTLOI."

"I told her I could not be a bridesmaid in her wedding because we were going to be hiking in Afghanistan that month, but truthfully it's just DTLOI."
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Dance The Shit Out Of It, as used in the classic dance film "Center Stage"
"All right, I wanna take it from the top. I want it full out. Look, just forget about the steps, just DTSOOI!"
DTSOOI by koopatroopanielson February 13, 2013
Related Words
dsoing DTLOI dtoi dtsof DTSOOI DTWOITNB
Down to suck or fuck
That girl is good to go. She is DTSOF fo sho!
dtsof by AmericanDonk May 23, 2018
The act of going to DSOI, with or without company, to a party or in general.
Hey! You want to go dsoing today?
dsoing by murga28 December 26, 2022

DTWOITNB 

An acronym meaning "Down to watch Orange is the New Black"
"Dude, if you're gonna marry her, she has to always be DTWOITNB."

"You're right."
DTWOITNB by ExtremeVolume August 12, 2014
Wanna be Boojie bitch straight outta 4th ward. Barbie like bitch. Swear she innocent and freaky den a mf. Will cut a bitch quick. Don’t have no kids but treats her niece and nephew like hers.
My Gutta Bitch DToi

Dtoi so 4th ward
dtoi by BigMeek November 23, 2021
It is said of the situation where a person has the bad luck to make contact with his testicles against an undefined surface or object, intentioned or not.
Given the nature of the word, it is more appropriate to design cases where the interaction is made with a moving object, for example, a ball.
Although it is extremely painful for the victim, it tends to be considerably funny to people who witness it.
Today in the baseball game the pitcher took a nutshot; the baseball hit him in the nuts.

Man, I just watched the funniest nutshot video ever.
Nutshot by Uberflaven March 1, 2009
Word of the Day on June 26, 2026